Comparison of ibuprofen versus celecoxib in post-extraction pain relief
DOI:
https://doi.org/10.61581/mjsp.v6i01.361Keywords:
Ibuprofen, Celecoxib, Pain relief, Post extraction, EfficacyAbstract
Objective: To compare mean pain score of celecoxib versus ibuprofen in post tooth extraction pain relief at a tertiary care hospital.
Methodology: The study was Quasi experimental design conducted in the Department of Oral and Maxillofacial Surgery, Jinnah Postgraduate Medical Centre, over a period of six months (July 2024 to January 2025). A total of 78 patients undergoing tooth extraction were enrolled and randomly allocated into two groups, with 39 patients in each group receiving either ibuprofen or celecoxib postoperatively. Pain intensity was assessed using the Visual Analogue Scale (VAS) at predefined intervals over a 24-hour postoperative period. Demographic data, including age, gender, and smoking status, were recorded and analyzed.
Results: The mean age of participants was 34.9 ± 8.0 years, with a near-equal gender distribution (52.6% male, 47.4% female). Most participants (59.0%) were from rural areas, and 24.4% were smokers. At 24 hours postoperatively, the celecoxib group reported significantly lower mean VAS scores (2.23 ± 1.36) compared to the ibuprofen group (3.37 ± 2.14) (p < 0.05), demonstrating superior analgesic efficacy.
Conclusion: Celecoxib provided significantly better pain relief than ibuprofen following tooth extraction, suggesting that selective COX-2 inhibition may offer an effective and well-tolerated alternative for postoperative analgesia in dental procedures.
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Copyright (c) 2025 Sundas Iqbal Aslam, Jehan Alam, Neha Joel, Ammara Siddiqui
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