Medical Journal of South Punjab
type: channel
description: The Medical Journal of South Punjab (MJSP) has been biannually published in Pakistan since 2020. It is a multi-disciplinary, peer-reviewed, open-access journal. MJSP has a team of highly qualified editorial board members who are dedicated to meet and improve the standards of the Journal as per the laid International guidelines. In addition, we are maintaining a multidisciplinary reviewers bank, which comprises of dedicated national and international researchers and subject specialists, who strive their best to evaluate the manuscript in the shortest possible time.
publisher: Medteach Private Limited.
language: en
publication name: Medical Journal of South Punjab
issn: 2708-2598
copyright: Authors retain copyright and grant the journal right of first publication with the work simultaneously licensed under a Creative Commons Attribution (CC-BY) 4.0 License that allows others to share the work with an acknowledgment of the work’s authorship and initial publication in this journal.
items: Treatment outcome in different classes of Lupus nephritis
items: Prevalence of pulmonary tuberculosis in end stage renal disease patients: A single center study
items: Evaluating the preoperative accuracy of multislice ct in determining resectability of periampullary pancreatic carcinoma
items: Frequency of peripheral nerve injury in oral and maxillofacial trauma
items: Intra-dialytic serum potassium changes among patients on maintenance hemodialysis thrice weekly
items: A study to assess quality of life in end stage renal disease patients undergoing hemodialysis: A single center study
items: Comparison of ibuprofen versus celecoxib in post-extraction pain relief
items: Incidence of common nerve injuries in patients with oral and maxillofacial trauma present at tertiary care hospital
items: Comparison between the efficacy of in-plane vs out-of-plane needle technique for ultrasound guided intravascular access
items: Efficacy of adjunctive corticosteroid therapy in severe community acquired pneumonia (SCAP) at a tertiary care hospital in Pakistan
items: Pattern of dentoalveolar injuries in trauma patients presenting in maxillofacial department of tertiary care hospital
items: The Frequency and Histological Type of Oral and Maxillofacial Malignancies Presenting at Tertiary Care Hospital
items: Pattern of Mandibular Fractures Presenting in Maxillofacial Department of Tertiary Care Hospital.
items: Prevalence of eczema in breast feed versus bottled feed
items: Comparison of outcome with 50% salicylic acid versus cryotherapy in the treatment of plantar warts
items: Correlation of creatine phosphokinase (CPK) levels with severity of organophosphate poisoning
items: Growth Assessment and Nutritional Profiling of School-Aged Children: A Cross-Sectional Study
items: Pudendal nerve block for post-opertive pain following per-anal surgeries in non-suppurative conditions
items: Effect of letrozole on shrinking the size of uterine fibroids in symptomatic patients of the reproductive age group
items: Comparison of effect of Fentanyl versus Esmolol on attenuation of hemodynamic response to laryngoscopy and endotracheal intubation
items: Comparing rubberband ligation vs sclerobanding for second degree hemorrhoids: A prospective comparative study
items: Increase in vessel luminal diameter after rotational atherectomy: a study from multan institute of cardiology, pakistan
items: Comparison of small versus large intracoronary thrombus burden on angiographic and short-term outcomes in patients undergoing primary PCI
items: The Role of Magnetic Resonance Imaging in the Intra-Operative Evaluation of Fistula in Ano
items: Comparison of solifenacin versus mirabegron for the treatment of double j stent related lower urinary tract symptoms
items: Correlation of Serum Immunoglobulin-E Level with Relapsing Idiopathic Nephrotic Syndrome in Children
items: Utilization of gram and oat flour cookies for diabetes
items: Effect of Post-operative Antibiotic Prophylaxis on Surgical Site Infections in Pediatric Inguinal Surgeries: A Randomized Controlled Trial
items: Comparison of short-term outcomes of open appendectomy and laparoscopic appendectomy in patients with acute appendicitis
items: Comparison of rubber band ligation and injection sclerotherapy for second degree hemorrhoids

Treatment outcome in different classes of Lupus nephritis
type: item
description: Objective: To evaluate treatment outcomes across different classes of lupus nephritis and to assess the association of baseline serum creatinine and proteinuria with remission status. Methodology: This prospective observational study included 157 adult patients with biopsy-proven lupus nephritis at a tertiary care center. Patients were classified according to the ISN/RPS classification and treated according to standard protocols based on LN class. Baseline demographics, clinical features, serum creatinine, proteinuria, complement levels, and anti-dsDNA antibodies were recorded. Outcomes were categorized as complete remission, partial remission, no response, or progression to end-stage renal disease (ESRD). Statistical analyses were performed using SPSS, with a significance level of p ? 0.05. Results: The cohort included predominantly female patients (84.1%), with a mean age of 33.8 ± 9.6 years. Class IV LN was the most frequent (38.9%), followed by Class III (24.8%) and Class V (14.0%). Complete remission was achieved in 38.2% of patients, partial remission in 38.9%, no response in 13.4%, and 9.6% progressed to ESRD. Patients achieving complete remission had significantly lower baseline serum creatinine (1.32 ± 0.48 vs 2.11 ± 0.74 mg/dL; p < 0.001) and proteinuria (2.41 ± 0.86 vs 4.12 ± 1.23 g/day; p < 0.001) compared with those with partial remission. Treatment outcomes differed significantly among LN classes (p < 0.001), with Class I and II showing the highest rates of complete remission and Class VI the poorest response. Conclusion: Histological class, baseline renal function, and proteinuria are key determinants of treatment outcomes in lupus nephritis. Patients with lower serum creatinine and proteinuria at presentation are more likely to achieve complete remission, highlighting the importance of early detection and aggressive management to improve renal prognosis.
subject: Medical Section
  topic: section
subject: Lupus nephritis
  topic: keywords
subject: Classes
  topic: keywords
subject: Treatment outcomes
  topic: keywords
subject: Nephrology
  topic: keywords
subject: Kidney
  topic: keywords
subject: Protienurea
  topic: keywords
subject: Remission
  topic: keywords
creator: Abdul Aziz
creator: Rashid Asgher
creator: Nayyar Saleem
creator: Zubair Ahmed
creator: Aimon Riaz
creator: Khuram Bashir
rights: Copyright (c) 2025 Abdul Aziz, Rashid Asgher, Nayyar Saleem, Zubair Ahmed, Aimon Riaz, Khuram Bashir https://creativecommons.org/licenses/by/4.0
date: 2025-12-24
publication date: 2025-12-24
starting page: 8
ending page: 16
doi: 10.61581/mjsp.v6i04.369

Prevalence of pulmonary tuberculosis in end stage renal disease patients: A single center study
type: item
description: Objective: To determine the prevalence of pulmonary tuberculosis and its associated factors among patients with end-stage renal disease at a single tertiary care center. Methodology: This cross-sectional study included 145 patients diagnosed with ESRD. Demographic data, clinical characteristics, comorbid conditions, and dialysis duration were recorded. Pulmonary tuberculosis was diagnosed based on clinical, radiological, and microbiological criteria. Data were analyzed using appropriate statistical tests, and a p-value ?0.05 was considered statistically significant. Results: The mean age of participants was 52.6 ± 13.4 years, with a male predominance (63.4%). The mean body mass index was 23.4 ± 3.2 kg/m². Hypertension was the most common comorbidity (74.5%), followed by diabetes mellitus (46.2%), ischemic heart disease (20%), and hepatitis C infection (15.2%). The overall prevalence of pulmonary tuberculosis among ESRD patients was 12.4%. PTB prevalence was significantly higher in patients undergoing dialysis for more than three years compared to those with a dialysis duration of three years or less (18.8% vs. 8.3%, p = 0.04). Conclusion: ESRD patients on maintenance dialysis are at substantially increased risk of PTB. In our cohort, the prevalence of 12.4% and the significant association with longer dialysis duration underscore the need for sustained screening and preventive strategies.
subject: Medical Section
  topic: section
subject: prevalence
  topic: keywords
subject: End stage renal disease
  topic: keywords
subject: pulmonary tuberculosis
  topic: keywords
subject: Dialysis
  topic: keywords
creator: Abdul Aziz
creator: Zubair Ahmed
creator: Rashid Asgher
creator: Aimon Riaz
creator: Nayyar Saleem
creator: Khuram Bashir
rights: Copyright (c) 2025 Abdul Aziz, Zubair Ahmed, Rashid Asgher, Aimon Riaz, Nayyar Saleem, Khuram Bashir https://creativecommons.org/licenses/by/4.0
date: 2025-12-23
publication date: 2025-12-23
starting page: 1
ending page: 8
doi: 10.61581/mjsp.v6i04.368

Evaluating the preoperative accuracy of multislice ct in determining resectability of periampullary pancreatic carcinoma
type: item
description: Objective: To determine the preoperative diagnostic accuracy of Multislice CT in determining Resectability of Periampullary Pancreatic Carcinoma. Methodology: This cross-sectional validation study was conducted in the Radiology Department, Pir Abdul Qadir Shah Jeelani Institute of Medical Sciences Gambat, from January 2025 to April 2025. Patients with clinically suspected periampullary pancreatic carcinoma who underwent preoperative MDCT followed by surgical exploration were included. Resectability on MDCT was assessed based on tumor-vessel relationship, local invasion, and metastatic spread. Imaging findings were compared with intraoperative and histopathological results to calculate sensitivity, specificity, positive predictive value (PPV), negative predictive value (NPV), and overall accuracy. Results: MDCT scan findings showed that 45 patients 76.3% had a clear tissue plane between the tumor and the superior mesenteric artery (SMA), and <180° SMV–PV involvement was seen in 64.4% patients. No evidence of metastasis was found in 74.6% patients. Other findings included abdominal ascites in 15.3%, SMA involvement in 22.0%, SMV–PV junction occlusion in 13.6%, liver metastasis in 11.9%, extra-pancreatic or peritoneal spread in 23.7%, and distant lymph node involvement in 22.0%. Conclusion: Multislice CT provides a reliable non-invasive modality for preoperative assessment of periampullary pancreatic carcinoma resectability, particularly in ruling out unresectable disease.
subject: Medical Section
  topic: section
subject: Periampullary pancreatic carcinoma
  topic: keywords
subject: Multislice CT
  topic: keywords
subject: Resectability
  topic: keywords
subject: Preoperative assessment
  topic: keywords
subject: Diagnostic accuracy
  topic: keywords
creator: Suhail Ahmed
creator: Munazza Zaffar
creator: Muhammad Irfan
creator: Habibullah Maitlo
creator: Liaqat Ali
creator: Jawad Ali
rights: Copyright (c) 2025 Suhail Ahmed, Munazza Zaffar, Muhammad Irfan, Habibullah Maitlo, Liaqat Ali, Jawad Ali https://creativecommons.org/licenses/by/4.0
date: 2025-06-30
publication date: 2025-06-30
starting page: 68
ending page: 75
doi: 10.61581/mjsp.v6i02.367

Frequency of peripheral nerve injury in oral and maxillofacial trauma
type: item
description: Objective: To assess the peripheral nerve injury incidence among patients suffering from oral and maxillofacial trauma. Methodology: This cross-sectional study included 100 patients presenting with maxillofacial trauma to the Department of Oral and Maxillofacial Surgery at Jinnah Postgraduate Medical Centre, Karachi, from 13th July 2024 to 12th January 2025. Data regarding demographics, etiology of trauma, site of injury, fracture type, and presence of peripheral nerve injury were collected. Trigeminal, facial, and concurrent nerve injuries were assessed clinically. Statistical analysis was performed to evaluate associations between nerve injuries and clinical variables. Results: The mean age of participants was 32.5 ± 11.4 years, with males comprising 72% of the sample. Road traffic accidents were the leading cause of trauma (54%), followed by assault (22%) and falls (12%). Peripheral nerve injury was present in 18% of patients. Trigeminal nerve injury occurred in 14%, facial nerve injury in 4%, and combined nerve injury in 2% of cases. A significant association was found between the presence of fractures and nerve injury (p < 0.05). Conclusion: Peripheral nerve injuries are a notable complication of oral and maxillofacial trauma account for 18% of patients, with trigeminal nerve involvement being more frequent than facial nerve injury.
subject: Medical Section
  topic: section
creator: Sundas Iqbal Aslam
creator: Jehan Alam
creator: Neha Joel
rights: Copyright (c) 2025 Sundas Iqbal Aslam, Jehan Alam, Neha Joel https://creativecommons.org/licenses/by/4.0
date: 2025-06-30
publication date: 2025-06-30
starting page: 48
ending page: 54
doi: 10.61581/mjsp.v6i02.366

Intra-dialytic serum potassium changes among patients on maintenance hemodialysis thrice weekly
type: item
description: Objective: To determine the mean change in serum potassium levels before and after the maintenance haemodialysis session. Methodology: A Quasi experimental study. Department of Nephrology,Sir Ganga Ram Hospital Lahore from 23-01-2025 to 22-04-2025. Total 110 patients were selected according to inclusion criteria. Age, gender, height, weight and comorbids were documented Serum potassium levels of MHD patients were checked before and just after the end of haemodialysis. The duration of dialysis was documented. Results: Mean duration of dialysis was 3.93 hours. Mean change in the potassium levels was 1.54±0.23 mmol/L. Mean change in potassium was compared between the groups based on age, BMI, gender and comorbs stratification, however, no statistically significant difference was observed (p>0.05). Paired t-test was applied for pre- and post-dialysis and the change was statistically significant (p<0.001). Conclusion: Maintenance hemodialysis session of 4 hours can significantly reduce serum potassium levels and subsequently reducing the risk of arrythmias due to hyperkalemia in ESRD patients.
subject: Medical Section
  topic: section
subject: Serum potassium
  topic: keywords
subject: Intradiallytic
  topic: keywords
subject: Hemodialysis
  topic: keywords
subject: Thrice weekly
  topic: keywords
creator: Umaar Azhar
creator: Shahid Anwar
creator: Sajad Ahmad Sajad Ahmad
creator: Hafiz Tahir Usman
creator: Adeela Alam
creator: Shehran Bilal
rights: Copyright (c) 2025 Umaar Azhar, Shahid Anwar, Sajad Ahmad, Hafiz Tahir Usman, Adeela Alam, Shehran Bilal https://creativecommons.org/licenses/by/4.0
date: 2025-09-30
publication date: 2025-09-30
starting page: 40
ending page: 45
doi: 10.61581/mjsp.v6i3.363

A study to assess quality of life in end stage renal disease patients undergoing hemodialysis: A single center study
type: item
description: Objective: To assess the quality of life in patients with end-stage renal disease (ESRD) undergoing maintenance hemodialysis and to identify factors influencing it. Methodology: Study was descriptive cross-sectional commenced at the Multan Institute of Kidney Diseases, Multan, from October 25, 2024, to April 24, 2025. Study included 100 patients with ESRD having age ?18 years, on hemodialysis from least three months. Main variables of study were demographics, duration of dialysis, vascular access type, co morbidities and the Kidney Disease Quality of Life Short Form (KDQOL-36) scale. Results: The mean age of participants was 49.2 ± 11.3 years, with 62% males and 38% females. Most patients (72%) received hemodialysis three times per week, and hypertension (68%) was the most common comorbidity. The mean score of physical and mental component were 43.25 ± 9.12 and 47.36 ± 8.74, respectively. Patients of young age on dialysis for ?12 months, and individuals without comorbidities had significantly higher quality of life scores (p < 0.05). Conclusion: Quality of life among ESRD patients on hemodialysis is moderately reduced, particularly in physical and psychological domains. Older age, prolonged dialysis duration, and comorbidities are key predictors of poor outcomes.
subject: Medical Section
  topic: section
subject: Quality of life
  topic: keywords
subject: End stage renal disease
  topic: keywords
subject: Hemodialysis
  topic: keywords
subject: Kidney
  topic: keywords
creator: Zubair Ahmed
creator: Abdul Aziz
creator: Muhammad Rashid Asgher
creator: Khuram Bashir
creator: Aimon Riaz
creator: Nayyar Saleem
rights: Copyright (c) 2025 Zubair Ahmed, Abdul Aziz, Muhammad Rashid Asgher, Khuram Bashir, Aimon Riaz, Nayyar Saleem https://creativecommons.org/licenses/by/4.0
date: 2025-09-30
publication date: 2025-09-30
starting page: 33
ending page: 39
doi: 10.61581/mjsp.v6i3.362

Comparison of ibuprofen versus celecoxib in post-extraction pain relief
type: item
description: Objective: To compare mean pain score of celecoxib versus ibuprofen in post tooth extraction pain relief at a tertiary care hospital. Methodology: The study was Quasi experimental design conducted in the Department of Oral and Maxillofacial Surgery, Jinnah Postgraduate Medical Centre, over a period of six months (July 2024 to January 2025). A total of 78 patients undergoing tooth extraction were enrolled and randomly allocated into two groups, with 39 patients in each group receiving either ibuprofen or celecoxib postoperatively. Pain intensity was assessed using the Visual Analogue Scale (VAS) at predefined intervals over a 24-hour postoperative period. Demographic data, including age, gender, and smoking status, were recorded and analyzed. Results: The mean age of participants was 34.9 ± 8.0 years, with a near-equal gender distribution (52.6% male, 47.4% female). Most participants (59.0%) were from rural areas, and 24.4% were smokers. At 24 hours postoperatively, the celecoxib group reported significantly lower mean VAS scores (2.23 ± 1.36) compared to the ibuprofen group (3.37 ± 2.14) (p < 0.05), demonstrating superior analgesic efficacy. Conclusion: Celecoxib provided significantly better pain relief than ibuprofen following tooth extraction, suggesting that selective COX-2 inhibition may offer an effective and well-tolerated alternative for postoperative analgesia in dental procedures.
subject: Medical Section
  topic: section
subject: Ibuprofen
  topic: keywords
subject: Celecoxib
  topic: keywords
subject: Pain relief
  topic: keywords
subject: Post extraction
  topic: keywords
subject: Efficacy
  topic: keywords
creator: Sundas Iqbal Aslam
creator: Jehan Alam
creator: Neha Joel
creator: Ammara Siddiqui
rights: Copyright (c) 2025 Sundas Iqbal Aslam, Jehan Alam, Neha Joel, Ammara Siddiqui https://creativecommons.org/licenses/by/4.0
date: 2025-03-30
publication date: 2025-03-30
starting page: 46
ending page: 51
doi: 10.61581/mjsp.v6i01.361

Incidence of common nerve injuries in patients with oral and maxillofacial trauma present at tertiary care hospital
type: item
description: Objective: To determine the frequency of common nerve injuries among patients presented with maxillofacial trauma. Methodology: The study was designed as a cross-sectional study and conductedin the Department of Oral and Maxillofacial Surgery at Jinnah Postgraduate Medical Centre, Karachi, from November 2023 to May 2024. A detailed history was obtained from each patient, followed by a clinical examination to identify any nerve involvement due to maxillofacial trauma. Radiological evaluation in the form of Orthopantomogram (OPG) and Paranasal Sinus (PNS) views was carried out to assess the presence of fractures and any associated nerve injuries. The type of nerve injury was confirmed through a comprehensive clinical assessment and history to detect involvement of the olfactory, infraorbital, inferior alveolar, and facial nerves. Results: Mean age was 32.4 ± 11.7 years. The majority of patients were male (70.0%), with females comprising 30.0% of the study population. In terms of type of nerve injury, the inferior dental nerve (IDN) was most commonly affected (44.6%), followed by the infraorbital nerve (ION) (28.5%), the facial nerve (18.5%), and the olfactory nerve (8.5%). Conclusion: This study's findings align with global trends in oral and maxillofacial nerve injuries, showing male predominance and high RTA-related trauma incidence, though assaults are more common in developed nations, reinforcing known trauma-nerve injury associations.
subject: Medical Section
  topic: section
subject: Incidence
  topic: keywords
subject: Nerve inury
  topic: keywords
subject: Oral
  topic: keywords
subject: Maxillofacial trauma
  topic: keywords
subject: Tertiary Care
  topic: keywords
creator: Sarfraz Ali
creator: Jehan Alam
creator: Ruqayah Shah
creator: Ahmad Sohail
rights: Copyright (c) 2024 Sarfraz Ali, Jehan Alam, Ruqayah Shah, Ahmad Sohail https://creativecommons.org/licenses/by/4.0
date: 2024-09-30
publication date: 2024-09-30
starting page: 42
ending page: 47
doi: 10.61581/mjsp.v5i03.360

Comparison between the efficacy of in-plane vs out-of-plane needle technique for ultrasound guided intravascular access
type: item
description: Objective: To compare the efficacy in terms of first pass success rate of in-plane vs out-of-plane needle technique for ultrasound guided central venous catheterization. Methodology: Randomized controlled trial was conducted at the Anesthesia Department, Shaikh Zayed Hospital Lahore, for a duration of 6 months i.e. from Jan 16, 2025 till June 15, 2025. After obtaining written informed consent, 280 patients who met the selection criteria were enrolled and were split into two equal-number groups using the lottery technique.i.e. 140 in each group. Patients in Group A underwent internal jugular vein catheterization via in-plane approach and Group B underwent out-of-plane approach. Outcomes were assessed and were statistically analyzed. Results: The mean age of the patients in Group A was 5211.49 years and in Group B was 5111.32 years. The mean time take for CVC in Group A was 557.71 seconds and in Group B was 427.29 seconds (p<0.001). The mean number of needle passes in Group A were 21.21 and in Group B were 10.55 (p=0.02). In Group A, the in-plane approach was efficacious in 87% patients compared to out-of-plane approach which was efficacious in 84.3% patients (p=0.495) Conclusion: There was no discernible difference in the effectiveness of the in-plane and out-of-plane approaches for CVC in patients undergoing heart surgery.
subject: Medical Section
  topic: section
subject: Cardiac surgical procedures
  topic: keywords
subject: In plane Needle
  topic: keywords
subject: out plane needle
  topic: keywords
subject: Catheterization
  topic: keywords
subject: Central venous
  topic: keywords
creator: Hira Khalil
creator: Riffat Zahid
creator: Unais Ahmed
creator: Syed Mehmood Ali
creator: Tayyaba Mumtaz
creator: Hafsa Hafeez Hafsa Hafeez
rights: Copyright (c) 2025 Hira Khalil, Riffat Zahid , Unais Ahmed, Syed Mehmood Ali , Tayyaba Mumtaz, Hafsa Hafeez https://creativecommons.org/licenses/by/4.0
date: 2025-09-30
publication date: 2025-09-30
starting page: 60
ending page: 68
doi: 10.61581/mjsp.v6i3.359

Efficacy of adjunctive corticosteroid therapy in severe community acquired pneumonia (SCAP) at a tertiary care hospital in Pakistan
type: item
description: Objective: To determine the adjunctive corticosteroid therapy in severe community acquired pneumonia (SCAP) at a tertiary care hospital in Pakistan. Methods: A randomized controlled trial was conducted at department of Pulmonology, Gujranwala Medical College / DHQ Gujranwala from 07-11-2024 to 06-05-2025. Sixty patients admitted in the department of pulmonologywere selected and divided into two groups. Group-A received only antimicrobial therapy and group-S received antimicrobial and 40?mg/day prednisone for 7 days as adjunctive therapy. Baseline data was recorded. Duration of antibiotics and hospital stay were also documented. Re-evaluation was done at seventh day of treatment and efficacy was assessed.Data was analyzed through SPSS version 25. Student t-test, chi square test or Fisher’s Exact test were applied. P ?0.05 was taken as statistically significant. Results: Duration of antibiotics therapy and hospitalization were significantly shorter in the steroid group (10.60±1.59 vs. 14.83±3.79 days, p<0.001; 11.43±2.03 days vs. 13.93±3.77 days, p=0.003, respectively). The outcome was better in the steroids group as compared to the antibiotics alone group (70% vs. 43.3%, p= 0.037). Conclusion: The use of corticosteroids has a beneficial role in improving the outcome and reducing the hospital stay among the elderly patients of severe community acquired pneumonia.
subject: Medical Section
  topic: section
subject: Corticosteroids
  topic: keywords
subject: Community aquired pneumonia
  topic: keywords
subject: Efficacy
  topic: keywords
subject: Pulmonology
  topic: keywords
creator: Asad Iqbal Khan
creator: Muhammad Younus
creator: Asim Saleem Sheikh
creator: Abdullah Khalid
creator: Ali Raza
creator: Hanzala Hanzala
rights: Copyright (c) 2025 Asad Iqbal Khan, Muhammad Younus, Asim Saleem Sheikh, Abdullah Khalid, Ali Raza, Hanzala https://creativecommons.org/licenses/by/4.0
date: 2025-09-30
publication date: 2025-09-30
starting page: 53
ending page: 59
doi: 10.61581/mjsp.v6i3.358

Pattern of dentoalveolar injuries in trauma patients presenting in maxillofacial department of tertiary care hospital
type: item
description: Objective: To determine the patterns of dentoalveolar injuries in patients presenting to the Maxillofacial Surgery Department of a tertiary care hospital. Methodology: The study employed a cross-sectional design and was conducted in the Department of Oral and Maxillofacial Surgery at Jinnah Postgraduate Medical Centre, Karachi, from December 2023 to June 2024. A detailed history and clinical examination, including extra-oral and intra-oral assessments, were conducted. Radiographic evaluations such as periapical, panoramic, and cone-beam CT scans were performed as needed. Injuries were classified according to Andreasen’s criteria. Results: Regarding the causes of nerve injury, road traffic accidents were the most common etiology, accounting for nearly half of the cases 49.7%, followed by assault 22.7%, falls 14.9%, epileptic seizures 9.4%, and firearm injuries 3.3%.The pattern of dentoalveolar injuries showed that enamel fractures were the most prevalent 24.9%, followed by root fractures 16.6%, subluxation and concussion 14.4%, dentine fractures 12.6%, extrusion 8.3%, crown fractures 6.6%, and intrusion 2.2%. Conclusion: Young males were predominantly affected by dentoalveolar trauma, with road traffic accidents and falls as the leading causes. Avulsion, subluxation, and luxation were the most common injury patterns.
subject: Medical Section
  topic: section
subject: Dentoalveolar injuries
  topic: keywords
subject: Pattern
  topic: keywords
subject: Maxillofacial
  topic: keywords
subject: Causes
  topic: keywords
subject: Etiology
  topic: keywords
creator: Ahmad Sohail
creator: Jehan Alam
creator: Ruqayah Shah
creator: Sarfraz Ali
rights: Copyright (c) 2024 Ahmad Sohail, Jehan Alam, Ruqayah Shah, Sarfraz Ali https://creativecommons.org/licenses/by/4.0
date: 2024-12-30
publication date: 2024-12-30
starting page: 56
ending page: 61
doi: 10.61581/mjsp.v5i04.356

The Frequency and Histological Type of Oral and Maxillofacial Malignancies Presenting at Tertiary Care Hospital
type: item
description: Objective: to determine the frequency of common types of oral and maxillofacial malignancies in patients presenting with malignant tumors at tertiary care hospital. Methodology: The study employed a descriptive cross-sectional design and was conducted in the Department of Oral and Maxillofacial Surgery at Jinnah Postgraduate Medical Centre, Karachi, from November 2023 to May 2024. The study focused on the histological types of oral and maxillofacial malignancies, which were classified based on cellular and tissue characteristics identified through microscopic examination. Data were collected using a customized proforma, recording biographical details and study variables such as frequency and histological typing based on histopathology reports. Results: The study included 175 patients, majority of the patients 85.1% aged >40 years. Tobacco use was prevalent among the study patients i.e. smoking 35.4%, pan 27.4%, and ghutka 22.9%. It was seen that squamous cell carcinoma 54.9% dominated carcinomas, followed by mucoepidermoid 24.6% and adenoid cystic 13.7%. Among sarcomas, Burkitt’s lymphoma 58.3% was most frequent, followed by osteosarcoma 34.9%. Conclusion: This study highlights the predominance of squamous cell carcinoma among carcinomas and Burkitt’s lymphoma among sarcomas, with significant age-related differences in sarcoma subtypes. The high prevalence of tobacco use underscores the need for targeted public health interventions to reduce modifiable cancer risk factors.
subject: Medical Section
  topic: section
subject: Frequency
  topic: keywords
subject: Maxillofacial Malignancies
  topic: keywords
subject: Squamous Cell Carcinoma
  topic: keywords
subject: Sarcoma
  topic: keywords
subject: Histology
  topic: keywords
creator: Sarfraz Ali
creator: Jehan Alam
creator: Ruqaya Shah
creator: Ahmad Sohail
rights: Copyright (c) 2024 Sarfraz Ali https://creativecommons.org/licenses/by/4.0
date: 2025-09-10
publication date: 2025-09-10
doi: 10.61581/mjsp.v5i02.352

Pattern of Mandibular Fractures Presenting in Maxillofacial Department of Tertiary Care Hospital.
type: item
description: Objective: This study will be conducted to evaluate the pattern of mandibular fractures presenting in maxillofacial department of tertiary care hospital. Methodology: The study was conducted in the Department of Oral and Maxillofacial Surgery at Jinnah Postgraduate Medical Centre, Karachi, over a period of six months from December 2023 to June 2024, after the synopsis was approved. A validated questionnaire was used to collect demographic data, including age, gender, and residential status, as well as details regarding the etiology of the fracture (e.g., road traffic accidents, falls, assaults, sports injuries) and fracture characteristics (location, type, and complexity). Results: Unilateral fractures 55.5% were more common than bilateral fractures 44.5%, with the angle 32.0% and body 26.5% being the most frequent fracture sites. Gender analysis showed no significant differences in fracture type (unilateral fractures: 53.5% in males vs. 60.7% in females, p=0.355) or fracture location (p=0.602), though males had a higher incidence of para-symphysis fractures 7.6% vs. 1.8%. Similarly, age stratification (18–40 years vs. 41–60 years) revealed no significant associations with fracture type or location. Conclusion: Mandibular fractures are a fairly common injury in severe trauma, primarily affecting young males. The most frequent sites of fracture are the mandibular angle, followed by the body and the condyle, while symphyseal, parasymphyseal and ramus fractures are relatively rare.
subject: Medical Section
  topic: section
subject: Trauma
  topic: keywords
subject: Pattern
  topic: keywords
subject: Mandible fracture
  topic: keywords
subject: Maxillofacial surgery
  topic: keywords
creator: Ahmad Sohail
creator: Jehan Alam
creator: Ruqayah Shah
creator: Sarfraz Ali
rights: Copyright (c) 2024 Ahmad Sohail, Jehan Alam https://creativecommons.org/licenses/by/4.0
date: 2024-09-30
publication date: 2024-09-30
starting page: 48
ending page: 53
doi: 10.61581/mjsp.v5i03.351

Prevalence of eczema in breast feed versus bottled feed
type: item
description: Objective: To compare the prevalence of eczema in infants who are exclusively breastfed versus those who are bottle-fed during the first six months of life. Methods: This cross-sectional study was conducted at Abbasi Shaheed Hospital, Karachi, Pakistan from 8 July 2023 to 7 January 2024 among infants aged 6 months to 2 years attending pediatric outpatient clinics. Feeding practices were recorded based on caregiver interviews, categorizing infants as either exclusively breastfed or bottle-fed. The diagnosis of eczema was made clinically by a pediatrician using standard diagnostic criteria. Statistical analysis was performed to compare the prevalence between the two groups. Results: In a study of 200 infants aged 1 month to 2 years, eczema prevalence was significantly higher in bottle-fed (28%) than breastfed (12%) children (p = 0.004). Among males, 28.6% of bottle-fed and 11.1% of breastfed had eczema (p = 0.016), while in females, rates were 27.3% and 13.0%, respectively (p = 0.046). Eczema was more common in bottle-fed infants across both normal BMI (17.2% vs. 7.3%, p = 0.047) and overweight categories (42.9% vs. 33.3%, p = 0.001). Conclusion: This study demonstrates a significantly higher prevalence of eczema among bottle-fed children compared to breastfed children aged 1 month to 2 years, highlighting the protective role of breastfeeding against early childhood eczema.
subject: Medical Section
  topic: section
subject: Eczema
  topic: keywords
subject: Breastfeed
  topic: keywords
subject: Bottled feed
  topic: keywords
subject: Children
  topic: keywords
subject: Allergies
  topic: keywords
creator: Ushna Fatima
creator: Shaheen Masood
creator: Syed Zaidan Shuja
creator: Taimoor Naeem Faridi
creator: Shafaq shahid
creator: Amber Naseer
rights: Copyright (c) 2024 Ushna Fatima, Shaheen Masood, Syed Zaidan Shuja , Taimoor Naeem Faridi, Shafaq shahid, Amber Naseer https://creativecommons.org/licenses/by/4.0
date: 2024-09-30
publication date: 2024-09-30
starting page: 1
ending page: 6
doi: 10.61581/mjsp.v5i03.349

Comparison of outcome with 50% salicylic acid versus cryotherapy in the treatment of plantar warts
type: item
description: Objective: “To compare the outcome of 50% salicylic acid versus cryotherapy in treating plantar warts.” Methodology: An RCT was conducted at the dermatology department of Nishtar Hospital, Multan, from August 1st, 2024, to January 31st, 2025. A total of 656 patients with plantar warts were randomly allocated to Group A (cryotherapy) and Group B (50% salicylic acid). All patients were evaluated at the conclusion of week 12 following the commencement of therapy. The outcome was classified as complete response (absence of warts), partial response (decreased number of warts), and no response after 12 weeks of treatment. The outcome was compared using a 5% significance level chi-square test, and a p-value of ? 0.05 was considered significant. Results: Both groups were comparable in terms of mean age, gender, duration of warts, and the number of warts. Group A had a higher complete response rate than Group B (30.8% vs. 24.7%; p = 0.134). No significant associations were found between patient response and study groups for age (p = 0.180), gender (p = 0.120), duration of warts (p = 0.249), or number of warts (p = 0.458). Conclusion: Our study concludes that cryotherapy had a better complete response rate than 50% salicylic acid at 12 weeks of therapy. Key Words: Cold Therapy; Cryotherapy; Human Papillomavirus; Salicylic Acid; Plantar Warts; Verruca; Warts;
subject: Medical Section
  topic: section
subject: Cold Therapy
  topic: keywords
subject: Cryotherapy
  topic: keywords
subject: Human Papillomavirus
  topic: keywords
subject: Salicylic Acid
  topic: keywords
subject: Plantar Warts
  topic: keywords
subject: Verruca
  topic: keywords
subject: Warts
  topic: keywords
subject: Plantar Warts
  topic: subjects
creator: Shoaib Iqbal
creator: Aliya Akhtar
creator: Raheel Tahir
creator: Sidra Tahir
creator: Amra Batool
creator: Asma Batool
rights: Copyright (c) 2025 Shoaib Iqbal, Aliya Akhtar, Raheel Tahir, Sidra Tahir, Amra Batool, Asma Batool https://creativecommons.org/licenses/by/4.0
date: 2025-09-30
publication date: 2025-09-30
starting page: 20
ending page: 25
doi: 10.61581/mjsp.v6i3.348

Correlation of creatine phosphokinase (CPK) levels with severity of organophosphate poisoning
type: item
description: Objective: To determine the correlation of creatine phosphokinase (CPK) levels with the severity of organophosphate poisoning in assessing the prognosis. Material and Methods: A cross-sectional study was conducted from January 9, 2025, to July 9, 2025, at the Department of Accident and Emergency, Mayo Hospital, Lahore. A total of 60 patients presenting with organophosphate poisoning were enrolled. The Peradeniya Organophosphate Compound Poisoning Scale (POP) assessed the severity of OP poisoning. Then, blood samples were collected for serum creatine phosphokinase. A comparison of CPK levels between mild to moderate and severe organophosphate poisoning was performed using a paired t-test. To find a correlation between CPK levels and the severity of OP poisoning (POP score), the Pearson correlation coefficient (r) was used. Results: The mean age was 37.63±13.48 years, with 55.0% of patients being under 40 years old. There were 78.3% males. The mean serum CPK level was 615.95±407.75 (IU/L). Patients with mild to moderate POP scores had a mean CPK level of 515.11 ± 248.65 IU/L, whereas those with severe scores had a significantly higher mean of 1374.33 ± 189.65 IU/L (p < 0.001). Pearson correlation analysis revealed a strong positive correlation between POP severity and CPK levels (r = 0.807, p < 0.001). Conclusion: Our study concluded that the creatine phosphokinase level is positively correlated with severe organophosphate poisoning, as measured by the POP scale. Key Words: Atropine; Creatine phosphokinase; Creatine kinase; Organophosphorus; Organophosphate; Organothiophosphonate Poisonings; Malathion;
subject: Medical Section
  topic: section
subject: Atropine
  topic: keywords
subject: Creatine phosphokinase
  topic: keywords
subject: Creatine kinase
  topic: keywords
subject: Organophosphorus
  topic: keywords
subject: Organophosphate
  topic: keywords
subject: Organothiophosphonate Poisonings
  topic: keywords
subject: Malathion
  topic: keywords
subject: Organophosphate Poisoning
  topic: subjects
creator: Awais Amin
creator: Layla Mazhar
creator: Abdul Shakoor Shakir
creator: Salman Raza
rights: Copyright (c) 2025 Awais Amin, Layla Mazhar, Abdul Shakoor Shakir, Salman Raza https://creativecommons.org/licenses/by/4.0
date: 2025-09-30
publication date: 2025-09-30
starting page: 26
ending page: 32
doi: 10.61581/mjsp.v6i3.347

Growth Assessment and Nutritional Profiling of School-Aged Children: A Cross-Sectional Study
type: item
description: Introduction: Childhood malnutrition, encompassing both undernutrition and overnutrition, is a major public health issue. Regular growth monitoring using anthropometric indices is vital to evaluate the nutritional status of school-aged children and to guide intervention strategies. Material & Methods: A cross-sectional study was carried out on a sample of 1300 school children. Data collected included age, height, weight, and BMI. Nutritional status was assessed using WHO growth standards for Weight-for-Height (WFH) and Height-for-Age (HFA). Children were categorized into Severe, Moderate, and Mild Malnutrition, Normal, Overweight, Obese+, and Obese++. Results: Of the 1300 children examined, 14.3% were identified with severe wasting, 25.1% with moderate wasting, and 30.5% with mild malnutrition. Only 20.2% of children fell within the normal range. Overweight and obesity were found in 7.0%, 2.5%, and 0.4% of the children respectively. Conclusion: A significant proportion of the study population exhibited malnutrition, with a majority falling into various categories of undernutrition and a considerable portion affected by overnutrition. These findings underscore the need for regular nutritional surveillance and targeted health programs to address the dual burden of malnutrition in school-aged children.
subject: Medical Section
  topic: section
subject: Child nutrition
  topic: keywords
subject: Growth assessment
  topic: keywords
subject: Malnutrition
  topic: keywords
subject: Weight-for-height
  topic: keywords
subject: Undernutrition
  topic: keywords
creator: Muhammad Naveed Mazhar
creator: Syed Hasan Danish
creator: Muhammad Zaeem Khalid
creator: Muhammad Karina Naveed
creator: Farah Ahmad
creator: Asghar Latif Shamsi
rights: Copyright (c) 2025 Muhammad Naveed Mazhar, Syed Hassan Danish, Muhammad Zeeshan Khalid, Muhammad Karina Naveed, Farah Ahmad, Asghar Latif Shamsi https://creativecommons.org/licenses/by/4.0
date: 2024-06-30
publication date: 2024-06-30
starting page: 40
ending page: 48
doi: 10.61581/mjsp.v6i02.241

Pudendal nerve block for post-opertive pain following per-anal surgeries in non-suppurative conditions
type: item
description: Objective: To compare patient outcomes of pain scores, time to first mobilization, need for intravenous opioids and mean hospital stay in patients receiving bilateral pudendal nerve block versus those receiving intravenous analgesia undergoing hemorrhoidectomy Methodology: This Quasi-experimental study was conducted at department of surgery, Combined Military Hospital, Multan from February 2024-December 2024. The patients were randomized into two groups of 80 patients each. Group A (n=80) to receive bilateral pudendal nerve block and Group-B (n=80) to receive intravenous analgesia in the form of opioids. Primary variables studied were median pain scores on the Visual Analog scale assessed at 6, 12, 24 and 36 hours. Secondary variables of study were need for rescue opioid analgesia and mean hospital stay. Mean total dose of IV Nalbuphine used till discharge was 13.44±5.87 mg versus 38.94±6.34 mg (p<0.001). Mean hospital stay was 2.35±0.48 days versus 3.76±0.55 days (p<0.001) Results: Median pain scores assessed post-operatively after spinal effect wore off showed that pain scores between both groups were 2.00 (1.00) versus 4.00 (2.00) at 6 hours (p<0.001), scores were 3.00 (1.00) versus 3.00 (1.00) at 12 hours (p=0.415), scores were 4.0 (1.00) versus 5.00 (1.00) at 24 hours (p<0.001) and scores were 4.00 (1.00) versus 4.00 (2.00) at 36 hours (p=0.081). Conclusion: The study concludes that PNB is associated with lesser pain scores, lesser duration of admission and lower need of opioids as rescue analgesia in patients undergoing hemorrhoidectomies.
subject: Medical Section
  topic: section
subject: Block
  topic: keywords
subject: hemorrhoids
  topic: keywords
subject: pain
  topic: keywords
subject: pudendal
  topic: keywords
subject: Surgery
  topic: subjects
subject: block
  topic: subjects
subject: hemorrhoids
  topic: subjects
subject: pudendal
  topic: subjects
creator: Afsa Nayyar
rights: Copyright (c) 2025 Afsa Nayyar https://creativecommons.org/licenses/by/4.0
date: 2025-10-01
publication date: 2025-10-01
doi: 10.61581/mjsp.v6i3.343

Effect of letrozole on shrinking the size of uterine fibroids in symptomatic patients of the reproductive age group
type: item
description: Objective: To compare the mean fibroid size (cm) before and after treatment with letrozole and the frequency of symptom improvement in symptomatic patients of the reproductive age group. Methodology: Quasi-experimental study was conducted between November 1st, 2024, and April 30th, 2025, at the Obstetrics and Gynaecology Department of Nishtar Hospital in Multan. Thirty women aged 25-45 who presented to the outpatient department were enrolled in this study. Throughout the trial, married women were encouraged to use barrier methods of contraception. Symptoms were graded according to the operational definition. Every woman took 5mg of the tablet Letrozole daily for three months. The myoma size before and after treatment, and the improvement of symptoms, were recorded. Results: The mean age of the study population was 34.70 ± 5.31 years. Most patients were married (76.7%, n=23), had 0–2 children (66.7%, n=20), and were non-obese (73.3%, n=22). Leiomyomas were primarily single in 63.3% (n=19) patients, with a mean size of 4.63 ± 1.22 cm, and 60.0% (n=18) exceeded 5 cm. Letrozole therapy significantly reduced uterine fibroid size from 5.37 ± 0.88 cm (pre-treatment) to 4.64 ± 0.70 cm (post-treatment), with a mean reduction of 0.73 cm (p=0.003). Among 30 patients, 66.7% (n=20) reported symptom improvement after letrozole therapy. Conclusion: Reduced uterus-leiomyoma size, improved control of related symptoms, and fewer adverse effects were observed after treatment with Letrozole. Key Words: Aromatase Inhibitors; Fibroid; Leiomyoma; Letrozole; Uterine fibroids;
subject: Medical Section
  topic: section
subject: Aromatase Inhibitors
  topic: keywords
subject: Fibroid
  topic: keywords
subject: Leiomyoma
  topic: keywords
subject: Letrozole
  topic: keywords
subject: Uterine fibroids
  topic: keywords
subject: Leiomyoma (ICD code: D25.9)
  topic: subjects
creator: Amara Malik
creator: Saima Ashraf
creator: Moiz Hassan Azdee
rights: Copyright (c) 2025 Amara Malik, Saima Ashraf, Moiz Hassan Azdee https://creativecommons.org/licenses/by/4.0
date: 2025-09-30
publication date: 2025-09-30
starting page: 13
ending page: 19
doi: 10.61581/mjsp.v6i3.340

Comparison of effect of Fentanyl versus Esmolol on attenuation of hemodynamic response to laryngoscopy and endotracheal intubation
type: item
description: Abstract Objective: This study aimed to compare the efficacy of esmolol and fentanyl in attenuating the hemodynamic response to laryngoscopy and endotracheal intubation. Methodology: A randomized controlled trial was conducted at CPEIC Multan, involving 194 patients undergoing elective surgery under general anesthesia. Patients were divided into two groups: Group A received 0.5 mg/kg of intravenous esmolol, and Group B received 1 mcg/kg of intravenous fentanyl, administered three minutes before intubation. Hemodynamic parameters, including heart rate (HR), systolic blood pressure (SBP), diastolic blood pressure (DBP), and mean arterial pressure (MAP), were recorded at baseline and five minutes post-intubation. Results: Both groups had comparable demographic and baseline hemodynamic characteristics. Post-intubation, Group A exhibited significantly lower HR (84.18±6.33 bpm) than Group B (96.72±5.39 bpm, p<0.001). Although SBP and DBP differences between the groups were not statistically significant (p=0.112 and p=0.229, respectively), MAP was significantly lower in Group B (92.48±8.44 mmHg) compared to Group A (96.14±6.89 mmHg, p=0.001). Conclusion: Esmolol was more effective in attenuating the tachycardic response to laryngoscopy and intubation, whereas fentanyl showed a greater effect on MAP reduction. These findings suggest esmolol may be preferable for controlling heart rate, while fentanyl may better manage blood pressure surges. Tailored dosing or adjunct therapies might be necessary for comprehensive hemodynamic control.
subject: Medical Section
  topic: section
creator: Salwa Sheeraz
creator: Kaneez Umme Farwa
rights: Copyright (c) 2025 Salwa Sheeraz, Kaneez Umme Farwa https://creativecommons.org/licenses/by/4.0
date: 2025-09-30
publication date: 2025-09-30
starting page: 6
ending page: 12
doi: 10.61581/mjsp.v6i3.342

Comparing rubberband ligation vs sclerobanding for second degree hemorrhoids: A prospective comparative study
type: item
description: Objective: To analyze the findings related to rubber band ligation versus sclerobanding in patients presenting with second degree hemorrhoids. Methodology: Quasi experimental study was conducted at surgery Department, Combined Military Hospital Multan from April 2024 to March 2025. A total of 260 patients belonging to both genders with second degree hemorrhoids were divided into two groups of 130 patients each. Patients in Group A underwent rubber band ligation while patients in Group received sclerobanding. The operative time was documented in both groups. Patients were followed up at 2, 4 and 8 weeks intervals for resolution of symptoms and any complications. SPSS version 25 was employed for data analysis, and a p-value below 0.05 was regarded as indicative of statistical significance. Results: The average age of participants in the study was 43.6 ± 11.4 years. The mean duration of surgery in the RBL group was 5.9 ± 2.0 minutes, compared to 9.4 ± 2.2 minutes in the sclerobanding group a difference that was statistically significant (p < 0.001). At 8 weeks follow up, complete resolution of symptoms was reported in 110 patients in Group A (84.6%) versus 121 patients (93.1%) in Group B. There was a statistically significant difference between the two groups (p = 0.030). At the 8-week follow-up, recurrence was observed in 7.7% of patients (10 individuals) in Group A, compared to 2.3% (3 individuals) in Group B—a difference that reached statistical significance (p = 0.046). Conclusion: Sclerobanding was found to be better than rubber band ligation alone in patients presenting with second degree hemorrhoids.
subject: Medical Section
  topic: section
subject: Hemorrhoids, postoperative pain, rubber band ligation, sclerobanding.
  topic: keywords
creator: Hamza Ali Malik
creator: Muhammad Ali Khan
creator: Rizwan Shabbir
creator: Muhammad Ibtisam Raza
creator: Abdullah Sher Kakar
creator: Hassan Shabbir
rights: Copyright (c) 2025 Dr. Hamza Ali Malik, Dr. Muhammad Ali Khan, Dr. Rizwan Shabbir, Dr. Muhammad Ibtisam Raza, Dr. Abdullah Sher Kakar, Dr. Hassan Shabbir https://creativecommons.org/licenses/by/4.0
date: 2025-09-30
publication date: 2025-09-30
doi: 10.61581/mjsp.v6i3.341

Increase in vessel luminal diameter after rotational atherectomy: a study from multan institute of cardiology, pakistan
type: item
description: Objective: To determine the increase in vessel luminal diameter in patients undergoing rotational atherectomy at Multan Institute of Cardiology, Pakistan. Material and Methods: A descriptive study enrolled 100 patients undergoing rotational atherectomy at Multan Institute of Cardiology, Pakistan. After baseline characteristics, the pre- and post-procedural minimal luminal diameter and reference vessel diameter were recorded. The change in luminal diameter was recorded in terms of mean and standard deviation. We stratified the data, applied a post-stratification t-test, and considered a p-value of less than 0.05 as significant. Results: The mean age was 52.20 ± 11.19 years, with more male (76.0%) patients. Risk factors included hypertension (45.0%), smoking (40.0%), diabetes (34.0%), and hyperlipidemia (32.0%). Lesions most frequently involved was the left anterior descending artery (LAD: 55.0%), with mid-distal location (65.0%) and severe calcification (71.0%). The minimal lumen diameter (MLD) significantly increased from pre-procedure and post-procedure 0.75?±?0.14?mm to 1.88?±?0.22?mm (p?<?0.001). At the same time, the mean luminal gain was 1.13±0.026?mm. The luminal gain with relation to reference diameter was 46%. Conclusion: Rotational atherectomy can lead to significant luminal gain with remarkable procedural success.
subject: Medical Section
  topic: section
subject: Rotablation
  topic: keywords
subject: Rotational Atherectomy
  topic: keywords
subject: Rotational Angioplasty
  topic: keywords
subject: Luminal Diameter
  topic: keywords
subject: Vessel Diameter
  topic: keywords
creator: Momin Rasheed
creator: Badar Ul Ahad Gill
creator: M. Ikram Farid
creator: Mubashir Sherwani
creator: Muhammad Shahzad Fareed
creator: Masood Ahmad Khan
rights: Copyright (c) 2025 Momin Rasheed, Badar Ul Ahad Gill, M. Ikram Farid, Mubashir Sherwani, Muhammad Shahzad Fareed, Masood Ahmad Khan https://creativecommons.org/licenses/by/4.0
date: 2024-06-30
publication date: 2024-06-30
starting page: 32
ending page: 39
doi: 10.61581/mjsp.v6i02.339

Comparison of small versus large intracoronary thrombus burden on angiographic and short-term outcomes in patients undergoing primary PCI
type: item
description: Objective: To compare the angiographic and short-term clinical outcomes of small vs. large intracoronary thrombus in patients undergoing Primary PCI. Methodology: A prospective comparative study was conducted at the CPEIC, Multan, from 10-04-2024 to 31-04-2025. Three hundred thirty patients with STEMI were enrolled, and the thrombus burden was analysed. Patients with thrombus grades of 0-2 were labelled as small thrombus burden (STB), and those with ?3 were considered large (LTB). The primary outcome variables were TIMI III flow (procedural success), 30-day mortality and 30-day re-infarction. Qualitative data was compared using the Chi-square test, and quantitative data with an independent t-test. Results: Out of 330 patients, there were 160 (48.5%) with STB and 170 (51.5%) with Large TB. No significant differences were observed in STEMI types (anterior wall: 58.1% vs. 60.0%, p=0.809; inferior wall: 32.5% vs. 29.4%) or culprit vessels (left anterior descending: 61.9% vs. 64.7%, p=0.765; right coronary artery: 32.5% vs. 31.2%). Mortality was higher in the STB group (11.9% vs. 5.9%, p=0.05), while re-infarction rates were comparable (8.8% vs. 7.1%, p=0.569). Procedural success (TIMI III flow) was significantly higher in STB (95.6% vs. 88.8%; p=0.022). Conclusion: Although the angiographic differences for thrombus burden were insignificant, small thrombus burden was associated with relatively more procedural success, 30-day mortality and 30-day reinfarction.
subject: Allied Section
  topic: section
subject: Acute Myocardial Infarction
  topic: keywords
subject: Intracoronary Thrombus
  topic: keywords
subject: No-reflow
  topic: keywords
subject: Primary Angioplasty
  topic: keywords
subject: Thrombus
  topic: keywords
subject: ST-elevation
  topic: keywords
creator: Muhammad Shahzad Fareed
creator: Muhammad Ikram Farid
creator: Badar Ul Ahad Gill
creator: Mubashir Sherwani
creator: Momin Rasheed
creator: Masood Ahmad Khan
rights: Copyright (c) 2025 Muhammad Shahzad Fareed, Muhammad Ikram Farid, Badar Ul Ahad Gill, Mubashir Sherwani, Momin Rasheed, Masood Ahmad Khan https://creativecommons.org/licenses/by/4.0
date: 2025-03-30
publication date: 2025-03-30
doi: 10.61581/mjsp.v6i01.338

The Role of Magnetic Resonance Imaging in the Intra-Operative Evaluation of Fistula in Ano
type: item
description: Abstract: Objective: assessing the role of magnetic resonance (MRI) imaging in intraoperative evaluation of fistula in ano. Study Type: Cross Sectional Analytical Study Study Place and Duration: Department of Radiology, Combined Military Hospital Gujranwala, from September 1, 2023 to August 30, 2024. Material and methods: Sixty patients were referred to the hospital's Radiology Department. Subsequently, these patients were referred for MRI scans in the Radiology Department. The MRI scanner used was equipped with a 16 channel body coil and a surface-coil. The data of all 60 patients who underwent surgical intervention were included in the study. The interval between MRI and surgery was from one week to two months. The gold standard was considered to be surgical findings, which were recorded independently by the surgeon. The researcher personally collected the data for the study and analyzed using SPSS version24. Continuous variables (age) were examined using descriptive statistics, namely; standard and mean deviation while categorical variables (gender) were using frequency and percentage. Results: Diagnostic performance indicated sensitivity (94.9%) and specificity (100.0%). The PPV was 100.0%, and the NPV was 25.0%, with an overall diagnostic accuracy of 95.0%. Conclusion: MRI offers precise anatomical and pathological information essential for directing pre-surgical decisions and planning in the management of perianal fistulas. Keywords: Magnetic Resonance Imaging (MRI), Intra-operative, Evaluation, Fistula in Ano, Accuracy, Sensitivity, Specificity.
subject: Medical Section
  topic: section
subject: Magnetic Resonance Imaging (MRI)
  topic: keywords
subject: Intra-operative
  topic: keywords
subject: Fistula in Ano
  topic: keywords
subject: Accuracy
  topic: keywords
subject: Sensitivity
  topic: keywords
subject: Specificity
  topic: keywords
subject: Magnetic Resonance Imaging (MRI)
  topic: subjects
subject: Intra-operative evaluation of fistula in ano
  topic: subjects
creator: Iqra Aslam Iqra
creator: Nadeem Ibrahim
creator: Naima Rauf
creator: Amer Hayat Haider
creator: Sadia Tahir
creator: Jahanzeb Javed
rights: Copyright (c) 2025 Iqra Aslam https://creativecommons.org/licenses/by/4.0
date: 2025-09-30
publication date: 2025-09-30
starting page: 77
ending page: 83
doi: 10.61581/mjsp.v6i02.337

Comparison of solifenacin versus mirabegron for the treatment of double j stent related lower urinary tract symptoms
type: item
description: Objective: Overactive bladder is mostly treated with a combination of behavioural interventions and commonly prescribed anti-muscarinic medication therapy, including solifenacin, which has considerable side effects and lowers the quality of life. Mirabegron relaxes the detrusor muscle and is a recently approved drug for the treatment of OAB. This study examined the effectiveness and safety of two medications, solifenacin and mirabegron. Methods: This study was a comparative cross-sectional study conducted at Sami Medical Center, Abbottabad for a period of 6 months from August 2022 to January 2023. Female patients of aged ?18 years with symptoms of OAB were enrolled. Results: Current study showed that the average age of patients was 37.47±12.48 years in Group S and 39.93±7.93 in Group M. The population consists of 60 (100%) females. After 4 weeks of follow up dizziness, dry mouth, constipation hypertension and blurred vision were found insignificant between both groups with p-values of 0.312, 0.161, 0.076, 0.076, and 0.313 respectively. OABSS score improved significantly and after therapy 4.20±1.32 in Group S and 3.43±1.13 in Group M. There was no significant difference in frequency of treatment withdrawal p-value 0.150. Conclusion:When it comes to relieving symptoms of OAB, both solifenacin and mirabegron are effective. The OABSS improved with both drugs; however, mirabegron was associated with fewer treatment-related adverse events. We advocate using mirabegron as the first-line treatment. Solifenacin can be utilized if patients are no longer getting the desired effects from Mirabegron.
subject: Medical Section
  topic: section
subject: Overactive bladder
  topic: keywords
subject: Mirabegron
  topic: keywords
subject: Urgency
  topic: keywords
subject: Solifenacin
  topic: keywords
creator: Ali Hussain
creator: Ali Imran Zaidi
rights: Copyright (c) 2025 Ali Hussain https://creativecommons.org/licenses/by/4.0
date: 2025-03-30
publication date: 2025-03-30
starting page: 52
ending page: 57
doi: 10.61581/MJSP.VOL06/01/07

Correlation of Serum Immunoglobulin-E Level with Relapsing Idiopathic Nephrotic Syndrome in Children
type: item
description: Objective: To correlate the relationship between the level of serum immunoglobulin-E in relapsing idiopathic nephrotic syndrome Methodology: We conducted this case-control study on 50 paediatric patients of both genders suffering from idiopathic nephrotic syndrome, who were aged between 2 and 12 years. Potential participants with a past history of urinary tract infections, non-nephrotic proteinuria, congenital nephrotic syndrome, secondary nephrotic syndrome, nephritic syndrome, and anatomical renal disorders were excluded. Patients were tested for serum Immunoglobulin E level. Results: Among the 50 participants, 29 (58.0%) were males, and 21 (42.0%) were females. 27 (54.0%) reported atopy in family. The mean age of the participants was 8.42 ± 2.81 years. The mean serum urea was 5.03 ± 1.33 mmol/L, and serum creatinine levels were 59.24 ± 11.47 µmol/L. The serum IgE levels were negatively correlated (r = -0.736, p<0.001). Similarly, serum IgE levels were negatively correlated (r = -0.408, p = 0.003). However, no statistically significant correlation was found among the serum IgE levels, serum urea, serum creatinine, gender, and family history. Conclusion: In children with idiopathic nephrotic syndrome, elevated serum IgE levels are linked to a higher chance of relapse later on.
subject: Medical Section
  topic: section
subject: Immune response
  topic: keywords
subject: Children
  topic: keywords
subject: Nephrotic syndrome
  topic: keywords
subject: Serum Immunoglobulin E
  topic: keywords
subject: Pediatrics
  topic: keywords
subject: Paediatrics
  topic: subjects
subject: Immunology
  topic: subjects
creator: Syed Awais Haider Kazmi
creator: Qudrat Ullah Malik
creator: Bilal Akhlaq
creator: Hafsa Arshad
creator: Zohaib Akhter
creator: Umair Anees
rights: Copyright (c) 2025 Syed Awais Haider Kazmi, Qudrat Ullah Malik, Bilal Akhlaq, Hafsa Arshad, Zohaib Akhter, Umair Anees https://creativecommons.org/licenses/by/4.0
date: 2025-06-30
publication date: 2025-06-30
starting page: 61
ending page: 67
doi: 10.61581/mjsp.v6i02.333

Utilization of gram and oat flour cookies for diabetes
type: item
description: Objective: To evaluate the nutritional, glycemic, and sensory attributes of cookies formulated with gram (chickpea) and oat flour for potential dietary management in individuals with type 2 diabetes mellitus. Methodology: This was experimental, randomized controlled trial (RCT). A total of 60 participants (aged 35–65) with diagnosed type 2 diabetes were enrolled. Patients were divided into two grouos. Group A (Intervention Group): Received 50g/day of gram and oat flour cookies. Group B (Control Group): Received 50g/day of standard refined wheat flour cookies. Results: Group A’s postprandial blood glucose fell from 198 ± 15 to 160 ± 14 mg/dL. Group B’s decreased from 196 ± 14 to 182 ± 15 mg/dL. These were also significant (p < 0.01). HbA1c in Group A declined from 7.8 ± 0.4% to 6.9 ± 0.3%. In Group B, it dropped from 7.7 ± 0.5% to 7.5 ± 0.4% (p < 0.05). Group A’s BMI reduced from 27.2 ± 1.5 to 26.5 ± 1.4 kg/m². Group B’s changed slightly from 27.1 ± 1.6 to 27.0 ± 1.5 kg/m². These were not statistically significant. The Intervention Cookie scored 8.1 (appearance), 7.9 (taste), 7.5 (texture), and 8.0 (overall). The Control Cookie scored slightly higher: 8.5, 8.4, 8.0, and 8.3, respectively. Conclusion: Cookies made from gram and oat flour showed significantly better glycemic outcomes compared to conventional cookies, with favorable sensory properties. The combination of high fiber and low GI ingredients may serve as a potential dietary adjunct for individuals with type 2 diabetes.
subject: Allied Section
  topic: section
subject: Diabetes
  topic: keywords
subject: Oat Flour
  topic: keywords
subject: Gram Floour
  topic: keywords
subject: Glycemic Index
  topic: keywords
subject: Utilization
  topic: keywords
creator: Noor-ul-Ain
creator: Syed iqtadar Ali Rizvi
creator: Samina Arshad
rights: Copyright (c) 2025 Noor-ul-Ain, Syed iqtadar Ali Rizvi, Samina Arshad https://creativecommons.org/licenses/by/4.0
date: 2025-04-12
publication date: 2025-04-12
doi: 10.61581/MJSP.VOL06/01/13

Effect of Post-operative Antibiotic Prophylaxis on Surgical Site Infections in Pediatric Inguinal Surgeries: A Randomized Controlled Trial
type: item
description: Objective: To determine the frequency of surgical site infections in pediatric patients undergoing elective inguinal surgeries with and without post-operative antibiotic prophylaxis. Methodology: This randomized controlled trial was conducted at the Department of Pediatric Surgery, Fatima Memorial Hospital, Shadman, Lahore, over six months. A total of 88 children aged 2–7 years undergoing elective inguinal herniotomy or orchidopexy were randomized into two groups of 44 each. All patients received a single pre-operative dose of intravenous Ceftriaxone (50 mg/kg). Group A received additional post-operative oral antibiotics (Amoxicillin-Clavulanic acid for five days), while Group B received no post-operative antibiotics. Patients were followed for 30 days post-operatively, and surgical wounds were assessed for signs of infection. Data were analyzed using SPSS version 25, with a p-value < 0.05 considered statistically significant. Results: The overall incidence of SSI was 5.7% (5 out of 88). Group A had 2 cases (4.5%) of SSI, while Group B had 3 cases (6.8%), a difference that was not statistically significant (p = 0.64). All infections were superficial and managed conservatively. No significant difference was found in hospital stay or severity of infections between the two groups. Conclusion: Routine post-operative antibiotic prophylaxis does not significantly reduce the risk of surgical site infections in clean elective pediatric inguinal surgeries. Judicious use of antibiotics is recommended to reduce the risk of antimicrobial resistance without compromising patient safety.
subject: Medical Section
  topic: section
subject: Surgical site infection
  topic: keywords
subject: Pediatric surgery
  topic: keywords
subject: Inguinal hernia
  topic: keywords
subject: Orchidopexy
  topic: keywords
subject: Antibiotics prophylaxis
  topic: keywords
creator: Sikandar Ali Arshad
creator: Syed Hassan Danish
creator: Muhammad Zaeem Khalid
creator: Khalid Maqsood
creator: Farah Ahmad
rights: Copyright (c) 2025 Sikandar Ali Arshad, Syed Hassan Danish, Muhammad Zaeem Khalid , Khalid Maqsood, Farah Ahmad https://creativecommons.org/licenses/by/4.0
date: 2025-06-30
publication date: 2025-06-30
starting page: 16
ending page: 23
doi: 10.61581/mjsp.v6i02.331

Comparison of short-term outcomes of open appendectomy and laparoscopic appendectomy in patients with acute appendicitis
type: item
description: Objective: To compare laparoscopic appendectomy and Open appendectomy in terms of short-term outcomes in patients with acute appendicitis. Methodology: Study was commenced at Department of Surgery at Ibn-e-Siena Hospital, Multan, as a randomized controlled trial over six months following the approval of the synopsis. A total of 60 patients, with 30 in each group, were included in the study using non-probability consecutive sampling. Patients were followed up weekly in the outpatient department for 30 days postoperatively. The occurrence of surgical site infection and seroma formation was assessed. Results: Mean duration of surgery of LA was significantly higher than OA, 63.13±3.28 minutes and 46.90±2.23 minutes, respectively (p<0.001). Mean duration of hospital stay of OA was significantly higher than OA, 3.03±0.92 days and 1.90±0.61 days, respectively (p<0.001). Surgical site infection was significantly higher in OA 12 (40.0%) than LA 3 (10.0%). (p=0.007). Whereas, seroma formation was observed in 6.7% OA and 3.3% in LA (p=0.129). Conclusion: Laparoscopic appendectomy offers advantages over open appendectomy in terms of reduced postoperative pain, shorter hospital stays, and lower wound infection rates, making it a preferred approach where feasible. However, the longer operative time and slightly higher risk of intra-abdominal abscess formation should be considered when selecting the surgical technique.
subject: Medical Section
  topic: section
subject: Appendectomy
  topic: keywords
subject: Laparoscopy
  topic: keywords
subject: Open surgery
  topic: keywords
subject: Hospital stay
  topic: keywords
creator: Warda Iram
creator: Humayun Amjad
creator: Bria Qaiser
rights: Copyright (c) 2025 Warda Iram, Humayun Amjad, Bria Qaiser https://creativecommons.org/licenses/by/4.0
date: 2025-03-30
publication date: 2025-03-30
starting page: 21
ending page: 26
doi: 10.61581/MJSP.VOL06/01/05

Comparison of rubber band ligation and injection sclerotherapy for second degree hemorrhoids
type: item
description: Objective: To compare the effectiveness of rubber band ligation (RBL) and sclerotherapy injection (SI) for 2nd degree hemorrhoids. Methodology: The study was conducted in the Department of General Surgery, Ibn-e-Siena Hospital, Multan, as a randomized controlled trial. It spanned a duration of six months following the approval of the study synopsis. The patients were randomly assigned to two groups (Group A and Group B) using the lottery method with sealed opaque envelopes. Group A consisted of patients who underwent hemorrhoidectomy using rubber band ligation, while Group B included those treated with injection sclerotherapy. All procedures were performed according to institutional protocols by consultant surgeons with a minimum of five years of post-fellowship experience. Results: The mean age of rubber band ligation and Injection sclerotherapy was 49.95±5.38 years and 47.66±6.01 years, respectively. (p=0.781). There were 73.4% males and 26.6% females in Group rubber band ligation and 65.6% males and 34.4% females, in Group sclerotherapy. (p=0.337). There were 15.6% obese in Group rubber band ligation and 21.9% obese in Group sclerotherapy. The mean duration of symptoms of Group rubber band ligation and Group sclerotherapy was 5.37±1.13 months, respectively. (p=0.198). Efficacy for Group rubber band ligation and Group sclerotherapy was 65.6% and 81.3%, respectively. (p=0.035). Conclusion: Rubber band ligation has been demonstrated to be superior to injection sclerotherapy in terms of effectiveness for the treatment of second-degree hemorrhoids, offering better outcomes in symptom resolution, reduced recurrence rates, and overall patient satisfaction while maintaining a minimally invasive approach with fewer complications.
subject: Medical Section
  topic: section
subject: Second degree hemorrhoids
  topic: keywords
subject: Rubber band ligation
  topic: keywords
subject: Sclerotherapy
  topic: keywords
subject: Efficacy
  topic: keywords
subject: Hemorrhoids
  topic: keywords
creator: Farwa Sarwar
creator: Noman Sarwar
creator: Mahrukh Rehman
creator: Saman Javaid
creator: Hassan Saeed
creator: Huda Khalid
rights: Copyright (c) 2025 Farwa Sarwar, Noman Sarwar, Mahrukh Rehman, Saman Javaid, Hassan Saeed , Huda Khalid https://creativecommons.org/licenses/by/4.0
date: 2025-03-30
publication date: 2025-03-30
starting page: 22
ending page: 27
doi: 10.61581/MJSP.VOL06/01/06